January 31, 2006There are a lot of infirmitys today, some distempers we know a lot about and are curable others are not; then in that respect are the diseases we just don?t know a lot about and have no redress. Scleroderma is a disease that we know a miniature bit about but have to cure. Patient and their families that do encounter the disease have questions. Questions like what is Scleroderma, we know there is no cure but is there treat manpowert for it, and what is the outlook?The word genus Scleroderma comes from deuce Greek words: ?sclero? convey hard, and ?derma? meaning skin. Scleroderma is an autoimmune disease of the connecter tissue. It is a chronic disease. ?Scleroderma is characterized by the nervous straination of bread tissue (fibrosis) in the skin and organs of the body.?(Medifocus, 2006) This leads to thickness and solution of involved areas. Scleroderma is in like manner referred to as systemic sclerosis.
The construct of Scleroderma is unknown. Fortunately, scleroderma is relatively uncommon affecting around 300,000 persons in the United States. The dis coiffe most commonly f every(prenominal)s in women between the ages of twenty and forty; however men and children lavatory be affected as well. The disease is not hereditary and is not thought to be inherited.
There are two categories of Scleroderma disseminate and limited. The diffuse form of scleroderma is involves proportionate thickening of skin of the extremities, face, trunk (chest, back, and abdomen) which can rapidly development to hardening after an early inflammatory phase. Organ disease can occur early on and be serious. organs affected include the esophagus, bowels, lungs (with scarring), heart, and kidneys.
The limited form of scleroderma tends to be toward the skin of the fingers and face. The skin changes and other features of disease tend to occur more slowly than in the diffuse form.
?The diagnosis of the scleroderma syndrome is based on the finding of the clinical features of the illnesses. Nearly all patients with scleroderma have blood tests which suggest autoimmunity, antinuclear antibodies (ANAs). A event antibody, the anticentromere antibody, is found almost exclusively in the limited form of scleroderma. Anti-Scl 70 antibody (antitopoisomerase I antibody) is most often seen in patients with the diffuse form of scleroderma.? (Medicine Net. Inc., 2006) Other tests are used to evaluate the front of any internal disease. These may include upper and cut back gastrointestinal tests to evaluate the bowels, chest x-rays, and lung function tests to examine the lungs, electrocardiogram and echocardiograms to evaluate the heart and lung arteries.
Currently there is no cure for Scleroderma. Even though there are no cures for the disease (or syndrome) there are treatment options. The treatment options depend on the location, or if it is diffused or limited. In general, medications that may be used include immunosuppressive agents, antifibrotic agents, anti-inflammatory agents, vasodilators, and angiotensin-converting enzyme inhibitors (Medifocus, 2006). In rare cases, when symptoms of systemic sclerosis become severe, surgery may be recommended.
The prognosis varies for patients depending on which caseful of scleroderma they have. Scientist says that it is often unenviable to rile a prognosis in the early stages of the disease. Scientist also say that the prognosis for patients with limited sclerosis who do not develop pulmonary hypertension is good; but men who develop the disease, patients with diffuse scleroderma, and patients who experience kidney, lung, and heart involvement mainly have a worse prognosis.
ReferencesMedifocus, (2006). Scleroderma. Retrieved January 7, 2007, from Scleroderma guide contain Website: hypertext transfer protocol://www.scleroderma-info.com/guide_detail.aspMedicine Net, (2006). Scleroderma, symptom and treatments. Retrieved January 7, 2007, fromScleroderma cancer Web site: http://www.medicinenet.com/scleroderma/index.htmKleinert, S., Tony, H.P., & Kneitz, C. (Oct 2006)Systemic sclerosis./SystemischeSklerose. In Der Internist, 47, p1051(12). Retrieved January 8, 2007, from HealthReference Center Academic via Thomson Gale: http://find.galegroup.com/itx/infomark.do?&contentSet=IACDocuments&type=retrieve&tabID
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